L-Valine → HCID 22859213, compound

Reaction equation

[NH2:1][C@H:2]([C:6]([OH:8])=[O:7])[CH:3]([CH3:5])[CH3:4].[C:9]([S:12][CH2:13][CH:14]([CH3:18])[C:15](Cl)=[O:16])(=[O:11])[CH3:10]>>[C:9]([S:12][CH2:13][CH:14]([CH3:18])[C:15]([NH:1][C@H:2]([C:6]([OH:8])=[O:7])[CH:3]([CH3:5])[CH3:4])=[O:16])(=[O:11])[CH3:10]

Participants

Reactant 2

HCID 6287L-Valine

HCID 103458Ethanethioic acid, S-(3-chloro-2-methyl-3-oxopropyl) ester

Product 1

HCID 22859213HCID 22859213, compound

Procedure

Following the procedure of Example 16, L-valine is reacted with 3-acetylthio-2-methyl-propanoyl chloride to give (±)-N-[3-(acetylthio)-2-methyl -1-oxopropyl]-L-valine.

Sources & evidence

ORD record: ord-47d38ee4e332419fa4ea702276086ad4
Source dataset: uspto-grants-1996_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05496805

Reaction notes

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