Toluene → tert-butyl methyl{[5-(3-methylpyridin-2-yl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}carbamate

HRID 144139

Reaction equation

HRID 144139 reaction equation
[Br:21][c:22]1[cH:23][c:24]([CH2:36][N:37]([C:38]([O:39][C:40]([CH3:41])([CH3:42])[CH3:43])=[O:44])[CH3:45])[cH:25][n:26]1[S:27](=[O:28])(=[O:29])[c:30]1[cH:31][n:32][cH:33][cH:34][cH:35]1.[CH3:1][c:2]1[c:3]([Sn:8]([CH2:9][CH2:10][CH2:11][CH3:12])([CH2:13][CH2:14][CH2:15][CH3:16])[CH2:17][CH2:18][CH2:19][CH3:20])[n:4][cH:5][cH:6][cH:7]1.[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[cH:53]1[cH:54][cH:55][c:56]([P:57]([Pd:58]([P:59]([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([P:78]([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[P:97]([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)([c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)([c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[c:122]2[cH:123][cH:124][cH:125][cH:126][cH:127]2)[cH:128][cH:129]1>>[CH3:1][c:2]1[c:3](-[c:22]2[cH:23][c:24]([CH2:36][N:37]([C:38]([O:39][C:40]([CH3:41])([CH3:42])[CH3:43])=[O:44])[CH3:45])[cH:25][n:26]2[S:27](=[O:28])(=[O:29])[c:30]2[cH:31][n:32][cH:33][cH:34][cH:35]2)[n:4][cH:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 164270983-Methyl-2-(tributylstannyl)pyridineHCID 57522258tert-Butyl {[5-bromo-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}methylcarbamateHCID 178420554HCID 178420554, compound

Product 1

HCID 66974667tert-butyl methyl{[5-(3-methylpyridin-2-yl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]methyl}carbamate

Sources & evidence

ORD record
ord-17bfbe6706da4bb78feb822f0cc5d172
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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