3-Fluorobenzenesulfonyl Chloride → N-(3-Methoxy-5-methyl-2-pyrazinyl)-3-fluorobenzenesulphonamide

Reaction equation

[CH3:1][O:2][C:3]1[C:4]([NH2:10])=[N:5][CH:6]=[C:7]([CH3:9])[N:8]=1.[F:11][C:12]1[CH:13]=[C:14]([S:18](Cl)(=[O:20])=[O:19])[CH:15]=[CH:16][CH:17]=1>>[CH3:1][O:2][C:3]1[C:4]([NH:10][S:18]([C:14]2[CH:15]=[CH:16][CH:17]=[C:12]([F:11])[CH:13]=2)(=[O:20])=[O:19])=[N:5][CH:6]=[C:7]([CH3:9])[N:8]=1

Participants

Reactant 2

HCID 27342583-Fluorobenzenesulfonyl Chloride

HCID 107018943-Methoxy-5-methyl-2-pyrazinamine

Product 1

HCID 10308383N-(3-Methoxy-5-methyl-2-pyrazinyl)-3-fluorobenzenesulphonamide

Procedure

Prepared by the method of Example 1 using 3-methoxy-5-methyl-2-pyrazinamine and 3-fluorobenzenesulphonyl chloride.

Sources & evidence

ORD record: ord-949b06a10a0e4855a995562439342fd0
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07662825B2

Reaction notes

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