Ethanolamine → HCID 10151176, compound

Reaction equation

[NH2:1][CH2:2][CH2:3][OH:4].[Cl:5][C:6]1[C:11]([Cl:12])=[CH:10][CH:9]=[CH:8][C:7]=1[S:13]([N:16]([C:25]1[C:30]([O:31][CH3:32])=[N:29][C:28](Cl)=[C:27]([Cl:34])[N:26]=1)COCC[Si](C)(C)C)(=[O:15])=[O:14]>>[Cl:5][C:6]1[C:11]([Cl:12])=[CH:10][CH:9]=[CH:8][C:7]=1[S:13]([NH:16][C:25]1[C:30]([O:31][CH3:32])=[N:29][C:28]([NH:1][CH2:2][CH2:3][OH:4])=[C:27]([Cl:34])[N:26]=1)(=[O:14])=[O:15]

Participants

Reactant 2

HCID 700Ethanolamine

HCID 11180148HCID 11180148, compound

Product 1

HCID 10151176HCID 10151176, compound

Procedure

Prepared by the method of Example 67 using 2-aminoethanol (0.05 g) and 2,3-dichloro-N-(5,6-dichloro-3-methoxy-2-pyrazinyl)-N-{[2-(trimethylsilyl)ethoxy]methyl}benzenesulfonamide (0.1 g). Yield 0.015 g.

Sources & evidence

ORD record: ord-0b375bcb83e84ed9afb1e4b13e446f0b
Source dataset: uspto-grants-2010_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07662825B2

Reaction notes

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