5-Phenylfuran-2-carboxylic acid → 1-Methyl-5-[(5-phenyl-furan-2-carbonyl)-amino]-1H-indole-2-carboxylic acid methyl ester

HRID 1444328

Reaction equation

HRID 1444328 reaction equation
[C:1]1([C:7]2[O:11][C:10]([C:12]([OH:14])=O)=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:15][O:16][C:17]([C:19]1[N:20]([CH3:29])[C:21]2[C:26]([CH:27]=1)=[CH:25][C:24]([NH2:28])=[CH:23][CH:22]=2)=[O:18]>>[CH3:15][O:16][C:17]([C:19]1[N:20]([CH3:29])[C:21]2[C:26]([CH:27]=1)=[CH:25][C:24]([NH:28][C:12]([C:10]1[O:11][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)=[CH:8][CH:9]=1)=[O:14])=[CH:23][CH:22]=2)=[O:18]

Participants

3

Reactant 2

HCID 7362555-Phenylfuran-2-carboxylic acidHCID 59654636HCID 59654636, compound

Product 1

HCID 596547541-Methyl-5-[(5-phenyl-furan-2-carbonyl)-amino]-1H-indole-2-carboxylic acid methyl ester

Procedure

Carboxylic acid (56) (23 mg, 0.12 mmol) was coupled to 5-amino-1-methyl-1H-indole-2-carboxylic acid methyl ester (25 mg, 0.12 mmol) using Method D to give the title compound.

Sources & evidence

ORD record
ord-a3e52e3090b84f458e4b1b200a7334e7
Source dataset
uspto-grants-2010_02
Patent number
US07662839B2

Linked notes

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