Water → HCID 178461152, compound
Reaction equation
[CH3:1][C@@H:2]1[C@@H:16]2[C:11](=[C:12]([OH:31])[C@:13]3([OH:30])[C:21](=[O:22])[C:20]([C:23]([NH2:25])=[O:24])=[C:19]([OH:26])[C@@H:18]([N:27]([CH3:29])[CH3:28])[C@@H:14]3[C@H:15]2[OH:17])[C:9](=[O:10])[C:8]2[C:7]([OH:32])=[CH:6][CH:5]=[CH:4][C:3]1=2.Cl.O>[Na+].[Cl-]>[CH3:1][C@@H:2]1[C@@H:16]2[C:11](=[C:12]([OH:31])[C@:13]3([OH:30])[C:21](=[O:22])[C:20]([C:23]([NH2:25])=[O:24])=[C:19]([OH:26])[C@@H:18]([N:27]([CH3:28])[CH3:29])[C@@H:14]3[C@H:15]2[OH:17])[C:9](=[O:10])[C:8]2[C:7]([OH:32])=[CH:6][CH:5]=[CH:4][C:3]1=2Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Double or triple transgenic animals were supplied for two weeks with doxycycline hydrochloride via drinking water (5% succrose, 0.2-2 mg Dox/ml) which was exchanged twice a week. For rapid and short-lived induction, 2 mg of Dox in 0.5 ml of 0.9% aqueous NaCl were injected i.p. Depending on the experiment injections were repeated twice in intervals of 24 hrs.
Workup
- waitwas exchanged twice a week
- customwere repeated twice in intervals of 24 hrs
Sources & evidence
- ORD record
- ord-0ebfa15ac8e746aa80a2507829d8978f
- Source dataset
- uspto-grants-2010_02
- Patent number
- US07666668B2
Reaction notes
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