Thionyl Chloride → 3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][S:10][CH2:11][CH:12]([CH3:16])[C:13](O)=[S:14])=[CH:5][CH:4]=1.S(Cl)([Cl:19])=O>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][S:10][CH2:11][CH:12]([CH3:16])[C:13]([Cl:19])=[S:14])=[CH:5][CH:4]=1

Participants

Reactant 2

HCID 24386Thionyl Chloride

HCID 178491718HCID 178491718, compound

Product 1

HCID 542258353-[[(4-Methoxy)phenylmethyl]thio]-2-methylthiopropionyl chloride

Procedure

3-[[(4-Methoxy)phenylmethyl]thio]-2-methylthiopropanoic acid prepared according to the procedure of Example 10 in U.S. Pat. No. 4,116,962 is treated with thionyl chloride to yield 3-[[(4-methoxy)phenylmethyl]-thio]-2-methylthiopropionyl chloride.

Sources & evidence

ORD record: ord-6614dae488124144a9422e514c270a19
Source dataset: uspto-grants-1982_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04316905

Reaction notes

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