Potassium Hydroxide → p-(2,4-Dimethoxybenzyloxy)aniline
Reaction equation
[CH3:1][O:2][C:3]1[CH:20]=[C:19]([O:21][CH3:22])[CH:18]=[CH:17][C:4]=1[CH2:5][O:6][C:7]1[CH:16]=[CH:15][C:10]([NH:11]C(=O)C)=[CH:9][CH:8]=1.[OH-].[K+]>C(O)C>[CH3:1][O:2][C:3]1[CH:20]=[C:19]([O:21][CH3:22])[CH:18]=[CH:17][C:4]=1[CH2:5][O:6][C:7]1[CH:16]=[CH:15][C:10]([NH2:11])=[CH:9][CH:8]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
p-(2,4-Dimethoxybenzyloxy)acetanilide (3 g, 0.01 M) in ethanol (30 ml) is treated with potassium hydroxide (3 g), then the mixture is heated under reflux for 12 hours. The solvent is removed by evaporation, the residue treated with water and extracted with ether. The ether solution is treated with charcoal, dried and concentrated to afford p-(2,4-dimethoxybenzyloxy)aniline.