4-Benzylideneaminopyridine → N-[alpha-(2-benzthiazolyl)benzyl]-4-pyridinamine

Reaction equation

[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[Li].[CH:11](=[N:18][C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH:11]([NH:18][C:19]1[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

Reactant 2

HCID 6428664-Benzylideneaminopyridine

HCID 178506775HCID 178506775, compound

Product 1

HCID 20380329N-[alpha-(2-benzthiazolyl)benzyl]-4-pyridinamine

Procedure

The title compound is prepared in a manner similar to Examples 5, 6 and 7 by reacting 2-benzthiazolyl lithium (formed by treating benzothiazole with butyl lithium) and 4-benzylideneaminopyridine.

Sources & evidence

ORD record: ord-135cf0490f064acda3d9adaa3dc4f58b
Source dataset: uspto-grants-1979_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04180670

Reaction notes

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