Sodium Hydroxide → HCID 23693686, compound
Reaction equation
[Br:1][C:2]1[CH:26]=[CH:25][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([O:16][CH3:17])=[CH:13][CH:14]=3)[C:9]([CH:18]([CH3:23])[CH2:19][C:20]([OH:22])=[O:21])=[C:8]2[CH3:24])=[CH:4][CH:3]=1.[OH-].[Na+:28]>CCO>[Br:1][C:2]1[CH:26]=[CH:25][C:5]([CH2:6][N:7]2[C:15]3[C:10](=[CH:11][C:12]([O:16][CH3:17])=[CH:13][CH:14]=3)[C:9]([CH:18]([CH3:23])[CH2:19][C:20]([O-:22])=[O:21])=[C:8]2[CH3:24])=[CH:4][CH:3]=1.[Na+:28]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A suspension of the acid from Step 5 (870 mg, 2.09 mmol) in 15 mL EtOH was treated with 1.00N NaOH (2.1 mL, 2.1 mmol), and stirred until the solid dissolved. The solution was concentrated to dryness, then dissolved in a minimum amount of water and freeze-dried to provide 914 mg of the title compound.