Cyclopentanepropanoic acid → 4-Cyclopentyl-1-cyclopentyl-butan-1-one

HRID 1453265Notes

Reaction equation

HRID 1453265 reaction equation
[CH:1]1([CH2:6][CH2:7][C:8](O)=O)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:11]1([CH2:17][CH2:18][C:19]([OH:21])=O)[CH2:16][CH2:15]CCC1>>[CH:1]1([CH2:6][CH2:7][CH2:8][C:19]([CH:18]2[CH2:15][CH2:16][CH2:11][CH2:17]2)=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 8818Cyclopentanepropanoic acidHCID 69702Cyclohexanepropanoic acid

Product 1

HCID 688687544-Cyclopentyl-1-cyclopentyl-butan-1-one

Procedure

The title compound was prepared analogously to Example A(44), where 3-cyclopentyl propionic acid was substituted in place of 3-cyclohexylpropionic acid in Step 1 of that example. 1H NMR (DMSO-d6): δ 0.79-0.91 (m, 2H), 1.11-1.24 (m, 5H), 1.55-1.88 (m, 12H), 2.41 (t, J=7.4, 2H), 2.81-2.91 (m, 1H).

Sources & evidence

ORD record
ord-dc82c4c6b9544923abccf14359aa783a
Source dataset
uspto-grants-2009_01
Patent number
US07473790B2

Reaction notes

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