1-(5-Trifluoromethyl-pyridin-2-yl)-piperazine → 9-{4-[4-(5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide
Reaction equation
[F:17][C:18]([CH2:19][NH:20][C:21](=[O:22])[C:23]1([CH2:36][CH2:37][CH2:38][CH2:39][Br:40])[c:24]2[cH:25][cH:26][cH:27][cH:28][c:29]2-[c:30]2[cH:31][cH:32][cH:33][cH:34][c:35]21)([F:41])[F:42].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[n:7][cH:8]1)([F:15])[F:16]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([N:9]2[CH2:10][CH2:11][N:12]([CH2:39][CH2:38][CH2:37][CH2:36][C:23]3([C:21]([NH:20][CH2:19][C:18]([F:17])([F:41])[F:42])=[O:22])[c:24]4[cH:25][cH:26][cH:27][cH:28][c:29]4-[c:30]4[cH:31][cH:32][cH:33][cH:34][c:35]43)[CH2:13][CH2:14]2)[n:7][cH:8]1)([F:15])[F:16]Participants
3
Sources & evidence
- ORD record
- ord-9766c8b43dec4854a0b7812fd3e69218
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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