Phenylacetyl chloride → 5-formyl-6-methoxy-N-(2-phenylacetyl)-3'-ureido-biphenyl-3-sulfonamide
Reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]([S:21]([NH2:24])(=[O:23])=[O:22])[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][C:18]([NH2:20])=[O:19])[CH:12]=2)[C:8]=1[O:9][CH3:10])=[O:2].[C:25]1([CH2:31][C:32](Cl)=[O:33])[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH:1]([C:3]1[CH:4]=[C:5]([S:21]([NH:24][C:32](=[O:33])[CH2:31][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)(=[O:23])=[O:22])[CH:6]=[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([NH:17][C:18]([NH2:20])=[O:19])[CH:12]=2)[C:8]=1[O:9][CH3:10])=[O:2]Participants
3
Procedure
Proceeding as in Reference 21, but substituting 5-formyl-6-methoxy-3′-ureido-biphenyl-3-sulfonamide and 2-phenylacetyl chloride, gave 5-formyl-6-methoxy-N-(2-phenylacetyl)-3′-ureido-biphenyl-3-sulfonamide.
Sources & evidence
- ORD record
- ord-e58713da80cd46a188512bd97f0c0c28
- Source dataset
- uspto-grants-2009_01