2-Chloro-4,6-dimethyl-3-nitropyridine → 1-{4-[(4,6-Dimethyl-3-nitro-2-pyridinyl)amino]phenyl}-2-propanol

HRID 1454581Notes

Reaction equation

HRID 1454581 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH:9]([OH:11])[CH3:10])=[CH:4][CH:3]=1.Cl[C:13]1[C:18]([N+:19]([O-:21])=[O:20])=[C:17]([CH3:22])[CH:16]=[C:15]([CH3:23])[N:14]=1>>[CH3:22][C:17]1[CH:16]=[C:15]([CH3:23])[N:14]=[C:13]([NH:1][C:2]2[CH:3]=[CH:4][C:5]([CH2:8][CH:9]([OH:11])[CH3:10])=[CH:6][CH:7]=2)[C:18]=1[N+:19]([O-:21])=[O:20]

Participants

3

Reactant 2

HCID 218755782-Chloro-4,6-dimethyl-3-nitropyridineHCID 218756721-(4-Aminophenyl)-2-propanol

Product 1

HCID 218757921-{4-[(4,6-Dimethyl-3-nitro-2-pyridinyl)amino]phenyl}-2-propanol

Procedure

The title compound was prepared according to the procedure described in step 3 of Example 1 from 1-(4-aminophenyl)-2-propanol (step 1) and 2-chloro-4,6-dimethyl-3-nitropyridine (step 2 of Example 1).

Sources & evidence

ORD record
ord-12a97445d6b64cc18d6ee8dc94919341
Source dataset
uspto-grants-2009_01
Patent number
US07479564B2

Reaction notes

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