2,4-Dichloro-6-methylbenzenesulfonyl chloride → 2,4-Dichloro-N-[6-(3-chloro-benzyloxymethyl)-pyridin-2-yl]-6-methyl-benzenesulfonamide

HRID 1454903

Reaction equation

HRID 1454903 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[CH2:5][O:6][CH2:7][C:8]1[N:13]=[C:12]([NH2:14])[CH:11]=[CH:10][CH:9]=1.[Cl:18][C:19]1[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([CH3:26])[C:20]=1[S:27](Cl)(=[O:29])=[O:28]>>[Cl:18][C:19]1[CH:24]=[C:23]([Cl:25])[CH:22]=[C:21]([CH3:26])[C:20]=1[S:27]([NH:14][C:12]1[CH:11]=[CH:10][CH:9]=[C:8]([CH2:7][O:6][CH2:5][C:4]2[CH:15]=[CH:16][CH:17]=[C:2]([Cl:1])[CH:3]=2)[N:13]=1)(=[O:29])=[O:28]

Participants

3

Reactant 2

HCID 28013872,4-Dichloro-6-methylbenzenesulfonyl chlorideHCID 688420116-(3-Chloro-benzyloxymethyl)-pyridin-2-ylamine

Product 1

HCID 688425992,4-Dichloro-N-[6-(3-chloro-benzyloxymethyl)-pyridin-2-yl]-6-methyl-benzenesulfonamide

Procedure

This material was prepared in analogy to example 1 from 6-(3-chloro-benzyloxymethyl)-pyridin-2-ylamine (0.08 g) and 2,4-dichloro-6-methyl-benzenesulfonyl chloride (0.092g) as a light yellow gum (0.039 g). MS (ESI−): 469.0 ([M−H]−).

Sources & evidence

ORD record
ord-7df92d556b0a45f983e61818edc32292
Source dataset
uspto-grants-2009_01
Patent number
US07482341B2

Linked notes

Loading…