1H-imidazole-2-carbaldehyde → HCID 57532141, compound

Reaction equation

[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH:6]=O.Cl.[F:9][CH:10]1[CH2:14][CH2:13][NH:12][CH2:11]1>>[F:9][CH:10]1[CH2:14][CH2:13][N:12]([CH2:6][C:2]2[NH:3][CH:4]=[CH:5][N:1]=2)[CH2:11]1

Participants

Reactant 2

HCID 249551H-imidazole-2-carbaldehyde

HCID 219752283-Fluoropyrrolidine hydrochloride

Product 1

HCID 57532141HCID 57532141, compound

Procedure

The title compound was prepared from 2-imidazolecarboxaldehyde and 3-fluoropyrrolidine hydrochloride using the synthetic procedure described for Intermediate 5.

Sources & evidence

ORD record: ord-2fcf75c225474968abf4fde5e24c577c
Source dataset: uspto-grants-2009_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07482374B2

Reaction notes

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