Bromotrimethylsilane → Diethyl [2-(4-chlorophenyl)ethenyl]phosphonate

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[CH:9][P:10]([O:15][CH2:16][CH3:17])(=[O:14])[O:11][CH2:12][CH3:13])=[CH:4][CH:3]=1.Br[Si](C)(C)C>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[CH:9][P:10]([OH:15])(=[O:11])[OH:14])=[CH:6][CH:7]=1.[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH:8]=[CH:9][P:10]([O:11][CH2:12][CH3:13])(=[O:14])[O:15][CH2:16][CH3:17])=[CH:6][CH:7]=1

Participants

Reactant 2

HCID 76113Bromotrimethylsilane

HCID 54328933Diethyl [2-(4-chlorophenyl)ethenyl]phosphonate

Product 2

HCID 54328933Diethyl [2-(4-chlorophenyl)ethenyl]phosphonate

HCID 54570726HCID 54570726, compound

Procedure

In this Example, the phosphonic acid derivative of diethyl 2-(4-chlorophenyl) ethenephosphonate 5b was prepared via reaction of 5b with bromotrimethylsilane.

Sources & evidence

ORD record: ord-78da0b5196e446ef8ef1de216da7c6b6
Source dataset: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05852198

Reaction notes

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