Veratraldehyde → 2-(3,4-Dimethoxy-alpha-hydroxybenzyl)benzaldehyde dimethylacetal
Reaction equation
[CH3:1][O:2][CH:3]([O:11][CH3:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1Br.[CH3:13][O:14][C:15]1[CH:16]=[C:17]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH:18]=[O:19]>>[CH3:1][O:2][CH:3]([O:11][CH3:12])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH:18]([OH:19])[C:17]1[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:15]([O:14][CH3:13])[CH:16]=1Participants
3
Procedure
2-bromobenzaldehyde dimethylacetal and 3,4-dimethoxybenzaldehyde are reacted in the same manner as described in Example 1-(1), whereby 2-(3,4-dimethoxy-α-hydroxybenzyl)benzaldehyde dimethylacetal is obtained as pale yellow syrup.
Sources & evidence
- ORD record
- ord-207c359cdc1043819b46424a88efd4d5
- Source dataset
- uspto-grants-1991_12