5,5-Dimethyl-4-thiazolidinecarboxylic acid → HCID 54322387, compound
Reaction equation
[CH2:1]([N:4]([CH2:10][CH:11]=O)[C:5](=[O:9])[O:6][CH2:7][CH3:8])[CH:2]=[CH2:3].[CH3:13][C:14]1([CH3:22])[S:18][CH2:17][NH:16][CH:15]1C(O)=O>C1(C)C=CC=CC=1>[CH3:13][C:14]1([CH3:22])[S:18][CH2:17][N:16]2[CH:15]1[CH2:3][CH:2]1[CH:11]2[CH2:10][N:4]([C:5]([O:6][CH2:7][CH3:8])=[O:9])[CH2:1]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
8.6 g (50 mmol) of ethyl N-allyl-N-(2-oxoethyl) -carbamate are heated under reflux overnight with 8.1 g (50 mmol) of 5,5-dimethylthiazolidine-4-carboxylic acid in 200 ml of toluene. The mixture is concentrated and the residue is distilled.
Workup
- concentrationThe mixture is concentrated
- distillationthe residue is distilled
Sources & evidence
- ORD record
- ord-099370b337774a45a13d0be893c78b65
- Source dataset
- uspto-grants-1991_12
- Patent number
- US05071999
Reaction notes
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