5,6-Dihydroquinoline → 5,6,7,8-Tetrahydro-7-dimethylaminoquinoline
Reaction equation
[Cl-].[CH3:2][NH2+:3][CH3:4].[N:5]1[C:14]2[CH:13]=[CH:12][CH2:11][CH2:10][C:9]=2[CH:8]=[CH:7][CH:6]=1>>[CH3:2][N:3]([CH3:4])[CH:12]1[CH2:13][C:14]2[N:5]=[CH:6][CH:7]=[CH:8][C:9]=2[CH2:10][CH2:11]1Participants
3
Procedure
This compound was prepared from dimethylammonium chloride (1.63 g, 20 mmol) and 5,6-dihydroquinoline (1.31 g, 10 mmol) using the experimental and purification method describes in Example 48. The product (0.72 g) was an oil which was identical to the compound isolated in Example 3.
Workup
- custompurification method
Sources & evidence
- ORD record
- ord-8cf27b10e2d64258a70bc63b4b0d63ed
- Source dataset
- uspto-grants-1991_12
- Patent number
- US05075303
Reaction notes
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