Reaction equation
C[O:2][C:3]([C:5]1[C:9]([NH:10][C:11](=[O:15])[CH:12](Cl)[CH3:13])=[CH:8][S:7][CH:6]=1)=[O:4].[C:16]([C:20]1[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=1)([CH3:19])([CH3:18])[CH3:17]>>[C:16]([C:20]1[CH:21]=[CH:22][C:23]([O:26][CH:12]([CH3:13])[C:11]([NH:10][C:9]2[C:5]([C:3]([OH:2])=[O:4])=[CH:6][S:7][CH:8]=2)=[O:15])=[CH:24][CH:25]=1)([CH3:19])([CH3:17])[CH3:18]Participants
3
Procedure
In analogy to Example 2, the title compound was prepared using rac-4-(2-chloro-propionylamino)-thiophene-3-carboxylic acid methyl ester and 4-tert-butylphenol. MS (m/e): 346.2 (M−H).
Sources & evidence
- ORD record
- ord-b040bc29c3e64f11820358c03ca818b1
- Source dataset
- uspto-grants-2010_06
- Patent number
- US07732452B2
Linked notes
Loading…