1,3-Dinitrobenzene → 3-Nitroanisole
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+]([O-])=O)[CH:5]=1)([O-:3])=[O:2].[CH3:13][O-:14].[Na+]>CN(P(N(C)C)(N(C)C)=O)C>[N+:1]([C:4]1[CH:5]=[C:6]([O:14][CH3:13])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]Participants
4
Reagents, catalysts & solvents 1
Procedure
m-Nitroanisole was prepared by reacting m-dinitrobenzene with sodium methoxide at 25° C. for 16 hours in hexamethylphosphotriamide solvent (N. Kornblum et al., J. Org. Chem., 41, 1560 (1976)).
Workup
- customat 25° C.
- customfor 16 hours
Sources & evidence
- ORD record
- ord-ed9cb278273043408beb7f1e17df48d2
- Source dataset
- uspto-grants-1991_12
- Patent number
- US05077436
Reaction notes
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