1,3-Dinitrobenzene → 3-Nitroanisole

HRID 1461899

Reaction equation

HRID 1461899 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+]([O-])=O)[CH:5]=1)([O-:3])=[O:2].[CH3:13][O-:14].[Na+]>CN(P(N(C)C)(N(C)C)=O)C>[N+:1]([C:4]1[CH:5]=[C:6]([O:14][CH3:13])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 74521,3-DinitrobenzeneHCID 10942334Sodium Methoxide

Product 1

HCID 111403-Nitroanisole

Reagents, catalysts & solvents 1

HCID 12679HexamethylphosphoramideSolvent

Procedure

m-Nitroanisole was prepared by reacting m-dinitrobenzene with sodium methoxide at 25° C. for 16 hours in hexamethylphosphotriamide solvent (N. Kornblum et al., J. Org. Chem., 41, 1560 (1976)).

Workup

  1. customat 25° C.
  2. customfor 16 hours

Sources & evidence

ORD record
ord-ed9cb278273043408beb7f1e17df48d2
Source dataset
uspto-grants-1991_12
Patent number
US05077436

Linked notes

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