1-(Trimethylsilyl)pyrrolidin-2-one → HCID 20452407, compound
Reaction equation
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[C:12](Cl)=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[Si](C)(C)[N:22]1[CH2:26][CH2:25][CH2:24][C:23]1=[O:27].C[O:31]C1C=CC(C(N2C(=O)C(O)CC2)=O)=CC=1>>[C:1]([O:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[O:18][CH3:19])[C:12]([N:22]1[CH2:26][CH2:25][CH2:24][C:23]1=[O:27])=[O:13])(=[O:31])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
4
Procedure
By heating equimolar amounts of 3-benzyloxy-4-methoxybenzoyl chloride and 1-trimethylsilyl-2-pyrrolidinone in an oil-bath of 100° C. in analogy to the procedure described in paragraph (b) of Example 9 there is obtained 1-(3-benzoyloxy-4-methoxybenzoyl)-2-pyrrolidinone. After stirring in diethyl ether and recrystallisation from ethyl acetate/n-hexane (3:1), the substance melts at 90.5°-91° C.