Hydrazine → 6-Morpholin-4-ylhexylamine
Reaction equation
[NH2:1]N.[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]C2C=CC=C3C(NC(=O)C=23)=O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1>CO>[N:3]1([CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][NH2:1])[CH2:4][CH2:5][O:6][CH2:7][CH2:8]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Hydrazine (aqueous solution at 35% by wt.) (0.15 ml; 1.6 mmoles) was added to 6-morpholinylhexylphthalimide (253 mg; 0.8 mmoles) in methanol (5 ml) and the resulting solution was refluxed. Reaction times and process as per Example 1.
Workup
- temperaturethe resulting solution was refluxed
- customReaction times and process as per Example 1
Sources & evidence
- ORD record
- ord-ef70946c3db44aac814f5608587536f9
- Source dataset
- uspto-grants-1994_04
- Patent number
- US05302593
Reaction notes
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