Diisobutylaluminumhydride → HCID 86747751, compound
Reaction equation
[CH2:1]1[CH2:22][O:21][CH:3]([CH2:4][C@H:5]2[C@H:12]([O:13][CH:14]3[CH2:19][CH2:18][CH2:17][CH2:16][O:15]3)[CH2:11][C@H:10]3[C@@H:6]2[CH2:7][C:8](=[O:20])[O:9]3)[O:2]1.[H-].C([Al+]CC(C)C)C(C)C>C1(C)C=CC=CC=1>[CH2:1]1[CH2:22][O:21][CH:3]([CH2:4][CH:5]2[CH:12]([O:13][CH:14]3[CH2:19][CH2:18][CH2:17][CH2:16][O:15]3)[CH2:11][CH:10]3[CH:6]2[CH2:7][CH:8]([OH:20])[O:9]3)[O:2]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
The ether (57) (4.700 g) was reduced in toluene (80 ml) at -78° C. with diisobutylaluminum hydride (1.5-M, 12 ml) to give the lactol (58).
Sources & evidence
- ORD record
- ord-400ff5d6789141b7a2b4c95548edbf20
- Source dataset
- uspto-grants-1994_04
- Patent number
- US05302617
Reaction notes
Loading…