Thiophosgene → 4-Methylthio-2-biphenylylisothiocyanate
Reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([S:8][CH3:9])[CH:5]=[CH:4][C:3]=1[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[C:16](Cl)(Cl)=[S:17]>O1CCOCC1.O>[CH3:9][S:8][C:6]1[CH:7]=[C:2]([N:1]=[C:16]=[S:17])[C:3]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)=[CH:4][CH:5]=1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Procedure
Reaction of 2-amino-4-methylthiobiphenyl (10.8 g) with thiophosgene (4.6 ml) in a mixture of dioxan (10 ml) and water (200 ml) at 10° C. and then at ambient temperature for 15 hours yielded 4-methylthio-2-biphenylylisothiocyanate as a yellow oil.
Sources & evidence
- ORD record
- ord-1b0c6b8c961540109926ec7f5150e84c
- Source dataset
- uspto-grants-1994_04
- Patent number
- US05302720
Reaction notes
Loading…