3,5-Dimethoxyaniline → HCID 53345204, compound

Reaction equation

[NH2:1][C:2]1[C:3]2[S:10][CH:9]=[C:8]([C:11]([NH:13][C:14]3[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=3[CH3:23])[C:17](O)=[O:18])=[O:12])[C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:24][O:25][C:26]1[CH:27]=[C:28]([CH:30]=[C:31]([O:33][CH3:34])[CH:32]=1)[NH2:29]>>[NH2:1][C:2]1[C:3]2[S:10][CH:9]=[C:8]([C:11]([NH:13][C:14]3[CH:15]=[C:16]([C:17](=[O:18])[NH:29][C:28]4[CH:30]=[C:31]([O:33][CH3:34])[CH:32]=[C:26]([O:25][CH3:24])[CH:27]=4)[CH:20]=[CH:21][C:22]=3[CH3:23])=[O:12])[C:4]=2[N:5]=[CH:6][N:7]=1

Participants

Reactant 2

HCID 663013,5-Dimethoxyaniline

HCID 67360239HCID 67360239, compound

Product 1

HCID 53345204HCID 53345204, compound

Procedure

The procedure of Step 5 of Example 1 was repeated except for using 3-(4-aminothieno[3,2-d]pyrimidine-7-carboxamido)-4-methylbenzoic acid obtained in Step 4 of Example 8 and 3,5-dimethoxyaniline to obtain the title compound (see Table 1).

Sources & evidence

ORD record: ord-07a28047dffb4d8b9288fe8f53d07c27
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08999973B2

Reaction notes

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