6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazine → 6-[4-(2,4-Difluorophenyl)piperazin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine
Reaction equation
[Cl:15][c:16]1[cH:17][cH:18][c:19]2[n:20]([n:21]1)[c:22]([C:25]([F:26])([F:27])[F:28])[n:23][n:24]2.[F:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][N:12]([c:16]3[cH:17][cH:18][c:19]4[n:20]([n:21]3)[c:22]([C:25]([F:26])([F:27])[F:28])[n:23][n:24]4)[CH2:13][CH2:14]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-b425d32ea5bc4cf19fbea4ad34952093
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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