2-Benzyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(1,6-Dibenzyl-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester

HRID 1466776

Reaction equation

HRID 1466776 reaction equation
[CH3:1][O:2][C:3](=[O:29])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16](Br)=[CH:17][CH:18]=3)[N:13]([CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[C:12]=2[CH3:28])[CH:5]=1.[CH2:30](B1OC(C)(C)C(C)(C)O1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>>[CH3:1][O:2][C:3](=[O:29])[C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([S:10][C:11]2[C:19]3[C:14](=[CH:15][C:16]([CH2:30][C:31]4[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=4)=[CH:17][CH:18]=3)[N:13]([CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[C:12]=2[CH3:28])[CH:5]=1

Participants

3

Reactant 2

HCID 38649642-Benzyl-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 667652363-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester

Product 1

HCID 667653893-(1,6-Dibenzyl-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester

Procedure

Prepared according to the procedure described in Example 11, Step 1, using the following starting materials: 3-(1-benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester and benzylboronic acid pinacol ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d6640821854740ff94a9b844f19084ae
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Linked notes

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