Chloroacetone → [3-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid ethyl ester

Reaction equation

[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([SH:12])[CH:7]=1)[CH3:2].Cl[CH2:15][C:16](=[O:18])[CH3:17]>>[CH2:1]([O:3][C:4](=[O:13])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][CH2:15][C:16](=[O:18])[CH3:17])[CH:7]=1)[CH3:2]

Participants

Reactant 2

HCID 6571Chloroacetone

HCID 66764945(3-Mercapto-phenyl)-acetic acid ethyl ester

Product 1

HCID 66764844[3-(2-Oxo-propylsulfanyl)-phenyl]-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 42, Step 1, using the following starting materials: (3-mercapto-phenyl)-acetic acid ethyl ester and chloroacetone.

Workup

customPrepared

Sources & evidence

ORD record: ord-28e8dfaee7844eecbf1f669b58592b02
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000025B2

Reaction notes

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