5-Chloropyridine-3-boronic acid → 3-[1-[4-(5-Chloro-3-pyridinyl)phenyl]ethyl]-6-(4-fluorophenyl)-6-(3-hydroxypropyl)-1,3-oxazinan-2-one
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:27])[O:12][C:13]([CH2:16][CH2:17][CH2:18][OH:19])([c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[Cl:28][c:29]1[cH:30][c:31]([B:35]([OH:36])[OH:37])[cH:32][n:33][cH:34]1>>[c:2]1(-[c:31]2[cH:30][c:29]([Cl:28])[cH:34][n:33][cH:32]2)[cH:3][cH:4][c:5]([CH:8]([CH3:9])[N:10]2[C:11](=[O:27])[O:12][C:13]([CH2:16][CH2:17][CH2:18][OH:19])([c:20]3[cH:21][cH:22][c:23]([F:26])[cH:24][cH:25]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-918af76c9adb41ee90794295918a8de5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…