Methanol → HCID 178446053, compound
Reaction equation
[CH3:1][N+:2]1([CH3:26])[C@@H:7]2[C@@H:8]3[O:10][C@@H:9]3[C@H:3]1[CH2:4][C@@H:5]([O:11][C:12]([C:14]([OH:25])([C:20]1[S:24][CH:23]=[CH:22][CH:21]=1)[C:15]1[S:19][CH:18]=[CH:17][CH:16]=1)=[O:13])[CH2:6]2.O.[Br-:28].[NH2:29][C@H:30]([C:35]([OH:37])=[O:36])[CH2:31][CH:32]([CH3:34])[CH3:33].CO>O>[CH3:1][N+:2]1([CH3:26])[C@@H:3]2[C@@H:9]3[O:10][C@@H:8]3[C@H:7]1[CH2:6][C@@H:5]([O:11][C:12]([C:14]([OH:25])([C:15]1[S:19][CH:18]=[CH:17][CH:16]=1)[C:20]1[S:24][CH:23]=[CH:22][CH:21]=1)=[O:13])[CH2:4]2.[OH2:36].[Br-:28].[NH2:29][C@H:30]([C:35]([OH:37])=[O:36])[CH2:31][CH:32]([CH3:34])[CH3:33]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
Tiotropium bromide (1.4 g) and L-leucine (0.5 g) were dissolved into methanol (60 ml). Water (60 ml) was added and shaken until dissolution occurred. The resultant solution was spray dried according to the parameters outlined above.