Methyl chloroglyoxylate → HCID 67258132, compound

Reaction equation

[OH:1]/[N:2]=[C:3](\[NH2:9])/[CH2:4][CH2:5][CH2:6][O:7][CH3:8].Cl[C:11](=O)[C:12]([O:14][CH3:15])=[O:13]>>[CH3:8][O:7][CH2:6][CH2:5][CH2:4][C:3]1[N:9]=[C:11]([C:12]([O:14][CH3:15])=[O:13])[O:1][N:2]=1

Participants

Reactant 2

HCID 79846Methyl chloroglyoxylate

HCID 24697443HCID 24697443, compound

Product 1

HCID 67258132HCID 67258132, compound

Procedure

In analogy to the procedure described for example D27 (1Z)—N′-hydroxy-4-methoxybutanimidamide (1.29 g), CaH2 (452 mg) and methyl chloro(oxo)acetate (1.32 g) yield the title compound as an oil.

Sources & evidence

ORD record: ord-3755d767888a4f95960ecff56a8fd396
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09018175B2

Reaction notes

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