5-Chloro-1-indanone → 1-Amino-5-chloroindane

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[C:9](Cl)[CH:10]=1)[CH:7]([NH2:12])[CH2:6][CH2:5]2.ClC1C=C2C(=CC=1)C(=O)CC2>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[CH:7]([NH2:12])[CH2:6][CH2:5]2

Participants

Reactant 2

HCID 1425995-Chloro-1-indanone

HCID 613828355,7-dichloro-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 148886021-Amino-5-chloroindane

Procedure

This compound was prepared using a method analogous to that of 5,7-dichloro-2,3-dihydro-1H-inden-1-amine (A.2.13), 5-chloro-1-indanone replacing 5,7-dichloro-1-indanone.

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-cb58939b00d148f3bc3e6ee27f6c0339
Source dataset: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09409917B2

Reaction notes

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