7-Bromo-2,3-dihydro-1H-inden-1-one → (7-Bromoindan-1-yl)amine

Reaction equation

Cl[C:2]1[CH:3]=[C:4]2[C:8](=[C:9](Cl)[CH:10]=1)[CH:7]([NH2:12])[CH2:6][CH2:5]2.[Br:13]C1C=CC=C2C=1C(=O)CC2>>[Br:13][C:9]1[CH:10]=[CH:2][CH:3]=[C:4]2[C:8]=1[CH:7]([NH2:12])[CH2:6][CH2:5]2

Participants

Reactant 2

HCID 145152987-Bromo-2,3-dihydro-1H-inden-1-one

HCID 613828355,7-dichloro-2,3-dihydro-1H-inden-1-amine

Product 1

HCID 66922464(7-Bromoindan-1-yl)amine

Procedure

This compound was prepared using a method analogous to that of 5,7-dichloro-2,3-dihydro-1H-inden-1-amine (A.2.13), 7-bromo-1-indanone replacing 5,7-dichloro-1-indanone.

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-8595263966724c6ba965a1212eecfb96
Source dataset: uspto-grants-2016_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09409917B2

Reaction notes

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