Pyridine → 3-bromo-N-[2-hydroxy-5-(trifluoromethyl)phenyl]isonicotinamide

HRID 148300

Reaction equation

HRID 148300 reaction equation
[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][n:9][cH:10]1.[NH2:11][c:12]1[c:13]([OH:22])[cH:14][cH:15][c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]1.[cH:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1>>[Br:1][c:2]1[c:3]([C:4](=[O:6])[NH:11][c:12]2[c:13]([OH:22])[cH:14][cH:15][c:16]([C:18]([F:19])([F:20])[F:21])[cH:17]2)[cH:7][cH:8][n:9][cH:10]1

Participants

4

Reactant 3

HCID 1049PyridineHCID 1202462-Amino-4-(trifluoromethyl)phenolHCID 8179723-Bromoisonicotinic acid

Product 1

HCID 668798803-bromo-N-[2-hydroxy-5-(trifluoromethyl)phenyl]isonicotinamide

Sources & evidence

ORD record
ord-9e32927a5b9f4b56a3d26ac067fa4d99
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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