3-Ethylamino-4-methylphenol → HCID 178463211, compound

HRID 1483234Notes

Reaction equation

HRID 1483234 reaction equation
[CH2:1]([NH:3][C:4]1[CH:5]=[C:6]([OH:11])[CH:7]=[CH:8][C:9]=1[CH3:10])[CH3:2].[CH:12]([C:14]1[CH:27]=[CH:26][C:17]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])=[CH:16][CH:15]=1)=O.[CH2:28]([N:30]1[C:39]2[C:34](=[CH:35][CH:36]=[C:37](O)[CH:38]=2)[C:33](C)=CC1(C)C)[CH3:29].C(C1C=CC(OCC(O)=O)=CC=1)=O>CO>[CH2:1]([NH:3][C:4]1[C:9]([CH3:10])=[CH:8][C:7]2[C:12]([C:14]3[CH:27]=[CH:26][C:17]([O:18][CH2:19][CH2:20][CH2:21][CH2:22][C:23]([OH:25])=[O:24])=[CH:16][CH:15]=3)=[C:36]3[C:37]([O:11][C:6]=2[CH:5]=1)=[CH:38]/[C:39](=[N:30]/[CH2:28][CH3:29])/[C:34]([CH3:33])=[CH:35]3)[CH3:2]

Participants

6

Reactant 4

HCID 84283-Ethylamino-4-methylphenolHCID 89177Acetic acid, 2-(4-formylphenoxy)-HCID 154511031-Ethyl-2,2,4-trimethyl-1,2-dihydroquinolin-7-olHCID 214628695-(4-Formylphenoxy)pentanoic acid

Product 1

HCID 178463211HCID 178463211, compoundYield 17%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

Dye 10 (shown below) was prepared using the procedure described in Example 4 except that 3-(ethylamino)-4-methylphenol and 5-(4-formylphenoxy)pentanoic acid substituted for 1-ethyl-2,2,4-trimethyl-1,2-dihydroquinolin-7-ol and 2-(4-formylphenoxy)acetic acid. Yield: 17%. λabs=524 nm (in methanol), λem=541 nm (in methanol).

Workup

  1. customDye 10 (shown below) was prepared

Sources & evidence

ORD record
ord-f961227f27cc4aaeabe09d2a8a01348e
Source dataset
uspto-grants-2016_08
Patent number
US09416153B2

Reaction notes

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