Ethanol → 4-Chloro-5-(cyclopentyloxy)-2-fluorobenzenamine

HRID 148959

Reaction equation

[CH3:23][CH2:24][OH:25].[Cl:1][c:2]1[cH:3][c:4]([F:19])[c:5]([NH:14][C:15](=[O:16])[O:17][CH3:18])[cH:6][c:7]1[O:8][CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1.[K+:21].[OH-:20].[OH2:22]>>[Cl:1][c:2]1[cH:3][c:4]([F:19])[c:5]([NH2:14])[cH:6][c:7]1[O:8][CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13]1

Participants

Reactant 5

HCID 702Ethanol

HCID 813Potassium Cation

HCID 961Hydroxide

HCID 962Water

HCID 15766845methyl N-(2-fluoro-4-chloro-5-cyclopentyloxyphenyl)carbamate

Product 1

HCID 152793894-Chloro-5-(cyclopentyloxy)-2-fluorobenzenamine

Sources & evidence

ORD record: ord-b19b6d5bf0d94ad8980759453028e9a3
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

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