1-Benzyl-3-pyrrolidinone → 1-Benzyl-3-[2-(4,4-dimethyl-2-oxazolin-2-yl)phenyl]-3-hydroxypyrrolidine
Reaction equation
[Br:14][c:15]1[c:16]([C:21]2=[N:25][C:24]([CH3:26])([CH3:27])[CH2:23][O:22]2)[cH:17][cH:18][cH:19][cH:20]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10](=[O:13])[CH2:11][CH2:12]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([OH:13])([c:15]2[c:16]([C:21]3=[N:25][C:24]([CH3:26])([CH3:27])[CH2:23][O:22]3)[cH:17][cH:18][cH:19][cH:20]2)[CH2:11][CH2:12]1Participants
3
Sources & evidence
- ORD record
- ord-2a765cb96041492cbe3c276dffd4d07a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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