1,4-Dioxa-8-azaspiro(4.5)decane → 6-(4,4-Ethylenedioxy-1-piperidinyl)-8-methyl-1,2,4-triazolo [4,3-b]pyridazine

HRID 1492403

Reaction equation

HRID 1492403 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH3:11])[C:5]2[N:6]([CH:8]=[N:9][N:10]=2)[N:7]=1.[CH2:12]1[CH2:21][O:20][C:14]2([CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)[O:13]1>>[CH2:12]1[CH2:21][O:20][C:14]2([CH2:19][CH2:18][N:17]([C:2]3[CH:3]=[C:4]([CH3:11])[C:5]4[N:6]([CH:8]=[N:9][N:10]=4)[N:7]=3)[CH2:16][CH2:15]2)[O:13]1

Participants

3

Reactant 2

HCID 674351,4-Dioxa-8-azaspiro(4.5)decaneHCID 40531136-Chloro-8-methyl-[1,2,4]triazolo[4,3-b]pyridazine

Product 1

HCID 232003096-(4,4-Ethylenedioxy-1-piperidinyl)-8-methyl-1,2,4-triazolo [4,3-b]pyridazine

Procedure

reacting 6-chloro-8-methyl-1,2,4,triazolo[4,3-b]pyridazine with 4,4-ethylenedioxypiperidine to give 6-(4,4-ethylenedioxy-1-piperidinyl) -8-methyl-1,2,4-triazolo[4,3-b]pyridazine;

Sources & evidence

ORD record
ord-dd3615c789564ed4a0bb833f5fa1e3ce
Source dataset
uspto-grants-1994_12
Patent number
US05374632

Linked notes

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