Chlorosulfamic acid → Sulfamic acid 4-phenoxybutyl ester

HRID 1493982Notes

Reaction equation

[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[O:6]([CH2:13][CH2:14][CH2:15][CH2:16][OH:17])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[O:6]([CH2:13][CH2:14][CH2:15][CH2:16][O:17][S:1](=[O:4])(=[O:3])[NH2:2])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Participants

Reactant 2

HCID 24499Chlorosulfamic acid

HCID 2196834-Phenoxybutan-1-ol

Product 1

HCID 53681636Sulfamic acid 4-phenoxybutyl esterYield 54%

Procedure

The title compound was prepared by procedures of Example 16 from sulfamoyl chloride and 4-phenoxy-1-butanol in 54% yield as an off-white solid, mp 76°-77° C.

Sources & evidence

ORD record: ord-e9e14c91bcbc478192f8058013974732
Source dataset: uspto-grants-1991_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05025031

Reaction notes

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