Chlorosulfamic acid → 2-(4-Chlorophenoxy)-2-methylpropanol sulfamate

Reaction equation

[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[Cl:6][C:7]1[CH:18]=[CH:17][C:10]([O:11][C:12]([CH3:16])([CH3:15])[CH2:13][OH:14])=[CH:9][CH:8]=1>>[Cl:6][C:7]1[CH:18]=[CH:17][C:10]([O:11][C:12]([CH3:15])([CH3:16])[CH2:13][O:14][S:1](=[O:4])(=[O:3])[NH2:2])=[CH:9][CH:8]=1

Participants

Reactant 2

HCID 24499Chlorosulfamic acid

HCID 191086602-(4-Chlorophenoxy)-2-methylpropan-1-ol

Product 1

HCID 197334572-(4-Chlorophenoxy)-2-methylpropanol sulfamateYield 58%

Procedure

The title compound was prepared by procedures of Example 16 from sulfamoyl chloride and 2-(4-chlorophenoxy)-2-methylpropanol to give a white solid, mp 76°-79° C., in 58% yield.

Workup

customto give a white solid, mp 76°-79° C.

Sources & evidence

ORD record: ord-9ae764c394e54e089e709db3f3b6be05
Source dataset: uspto-grants-1991_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05025031

Reaction notes

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