Reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][CH2:9][C:10]([SH:13])([CH3:12])[CH3:11].[CH2:14]([S:18][C:19]([CH3:23])([CH3:22])[CH:20]=O)/[CH:15]=[CH:16]/[CH3:17]>>[CH2:14]([S:18][C:19]([CH3:23])([CH3:22])[CH2:20][NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][CH2:9][C:10]([SH:13])([CH3:11])[CH3:12])/[CH:15]=[CH:16]/[CH3:17]Participants
3
Procedure
2-Amino-1-(2-mercapto-2-methylpropylamino)benzene (0.36 g, 1.84×10-3 mol) and 0.58 g (3.67×10-3 mol, 200 M %) 2-(trans-2-butenylthio)-2-methylpropanal were reacted by the procedures in Example 2 to give 0.55 g (88% yield) 1-[2-(trans-2-butenylthio)-2-methylpropylamino]-2-(2-mercapto-2-methylpropylamino)benzene as an oil after purification by radial chromatography on a 4 mm silica plate eluting with 100% hexane.
Sources & evidence
- ORD record
- ord-44e9e6a07a344ae680c5e5a44a2b4782
- Source dataset
- uspto-grants-1991_06
- Patent number
- US05026913
Linked notes
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