4-Hydroxyphenylacetone → N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine

HRID 150328

Reaction equation

[OH:14][c:15]1[cH:16][cH:17][c:18]([CH2:21][C:22]([CH3:23])=[O:24])[cH:19][cH:20]1.[OH:1][CH:2]([CH2:3][NH2:4])[c:5]1[n:6][c:7]([C:10]([F:11])([F:12])[F:13])[s:8][cH:9]1>>[OH:1][CH:2]([CH2:3][NH:4][CH:22]([CH2:21][c:18]1[cH:17][cH:16][c:15]([OH:14])[cH:20][cH:19]1)[CH3:23])[c:5]1[n:6][c:7]([C:10]([F:11])([F:12])[F:13])[s:8][cH:9]1

Participants

Reactant 2

HCID 70192744-Hydroxyphenylacetone

HCID 140762394-Thiazolemethanol, alpha-(aminomethyl)-2-(trifluoromethyl)-

Product 1

HCID 19974300N-[2-(4-Hydroxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-trifluoromethylthiazol-4-yl)ethanamine

Sources & evidence

ORD record: ord-d8c9dfa1186f48aba409d1953c3d9f87
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

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