Acetic Acid → 1-{1-[(5-Chlorothiophen-2-yl)methyl]piperidin-4-yl}-7-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-h][1,6]naphthyridin-4(7H)-one

Reaction equation

[NH:1]1[CH2:6][CH2:5][CH:4]([N:7]2[C:16]3[C:11](=[CH:12][N:13]=[C:14]4[N:19]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:27])([CH3:26])[CH3:25])[CH:18]=[CH:17][C:15]4=3)[C:10](=[O:28])[CH:9]=[CH:8]2)[CH2:3][CH2:2]1.[Cl:29][C:30]1[S:34][C:33]([CH:35]=O)=[CH:32][CH:31]=1.B.N1C=CC=CC=1C.C(O)(=O)C>CO>[Cl:29][C:30]1[S:34][C:33]([CH2:35][N:1]2[CH2:6][CH2:5][CH:4]([N:7]3[C:16]4[C:11](=[CH:12][N:13]=[C:14]5[N:19]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:25])([CH3:27])[CH3:26])[CH:18]=[CH:17][C:15]5=4)[C:10](=[O:28])[CH:9]=[CH:8]3)[CH2:3][CH2:2]2)=[CH:32][CH:31]=1