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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15095Generated: October 23, 2026

1,4-Butanediol → Tert-butyl 2-(4-hydroxybutoxymethyl)-6-methylbenzoate

https://huagongshe.com/en/reaction/15095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-ButanediolHCID 8064—
ReactantTert-butyl 2-(3-hydroxypropoxymethyl)-6-methylbenzoateHCID 59341259—
Reactanttert-Butyl 2-(bromomethyl)-6-methylbenzoateHCID 59341261—
ProductTert-butyl 2-(4-hydroxybutoxymethyl)-6-methylbenzoateHCID 59341263—

Reaction Steps

tert-Butyl 2-(4-hydroxybutoxymethyl)-6-methylbenzoate is prepared from tert-butyl 2-bromomethyl-6-methylbenzoate and butane-1,4-diol in analogy to the synthesis of tert-butyl 2-(3-hydroxypropoxymethyl)-6-methylbenzoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732471B2
Source datasetuspto-grants-2010_06
ORD IDord-a3f13bbb3b6247e4939028582f7ce2db
Source noteuspto-grants-2010_06