Sodium Ion → 3-Dimethylaminomethyl-4-chloro-5-benzyloxy-indole

Reaction equation

[CH3:1][C:2](=[O:3])[Cl:4].[CH3:5][N:6]([CH3:7])[CH2:8][N:9]([CH3:10])[CH3:11].[Cl:12][c:13]1[c:14]2[cH:15][cH:16][nH:17][c:18]2[cH:19][cH:20][c:21]1[O:22][CH2:23][c:24]1[cH:25][cH:26][cH:27][cH:28][cH:29]1.[Cl:32][CH2:33][Cl:34].[Na+:31].[OH-:30]>>[CH2:8]([N:9]([CH3:10])[CH3:11])[c:15]1[c:14]2[c:13]([Cl:12])[c:21]([O:22][CH2:23][c:24]3[cH:25][cH:26][cH:27][cH:28][cH:29]3)[cH:20][cH:19][c:18]2[nH:17][cH:16]1

Participants

Reactant 6

HCID 923Sodium Ion

HCID 961Hydroxide

HCID 5829N,N,N',N'-Tetramethylmethanediamine

HCID 6344Dichloromethane

HCID 6367Acetyl chloride

HCID 233731004-Chloro-5-benzyloxyindole

Product 1

HCID 233730643-Dimethylaminomethyl-4-chloro-5-benzyloxy-indole

Sources & evidence

ORD record: ord-18fa0ac0226649f1a69e6a899d54745f
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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