3,5-dichloro-N-(1-methyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-phenylsulphonamide → 5-Amino-1-methyl-2-oxoindoline
Reaction equation
ClC1C=C(S([NH:12][C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[N:18]([CH3:22])[C:17](=[O:23])[CH2:16]3)(=O)=O)C=C(Cl)C=1>CO>[NH2:12][C:13]1[CH:14]=[C:15]2[C:19](=[CH:20][CH:21]=1)[N:18]([CH3:22])[C:17](=[O:23])[CH2:16]2Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The reaction is carried out in methanol. The crude product is further reacted directly in V (5).
Sources & evidence
- ORD record
- ord-188f16347e2d4126b658ee9cf10e8665
- Source dataset
- uspto-grants-2012_07
- Patent number
- US08211923B2
Reaction notes
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