Sodium Carbonate → [3-Methyl-5-(2-trifluoromethyl-phenyl)-pyridin-2-yl]-(4-pyrrolidin-1-yl-piperidin-1-yl)-methanone

Reaction equation

COC(C1C(C)=CC(C2C=CC=C([C:18]([F:21])([F:20])[F:19])C=2)=CN=1)=O.Cl[C:23]1[CH:24]=[C:25]([C:30]2[CH:31]=[C:32]([CH3:49])[C:33]([C:36]([N:38]3[CH2:43][CH2:42][CH:41]([N:44]4[CH2:48][CH2:47][CH2:46][CH2:45]4)[CH2:40][CH2:39]3)=[O:37])=[N:34][CH:35]=2)[CH:26]=[CH:27][C:28]=1Cl.FC(F)(F)C1C=CC=CC=1B(O)O.C(=O)([O-])[O-].[Na+].[Na+]>O1CCOCC1.O.[Pd](Cl)Cl>[CH3:49][C:32]1[C:33]([C:36]([N:38]2[CH2:43][CH2:42][CH:41]([N:44]3[CH2:48][CH2:47][CH2:46][CH2:45]3)[CH2:40][CH2:39]2)=[O:37])=[N:34][CH:35]=[C:30]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:23][C:24]=2[C:18]([F:21])([F:20])[F:19])[CH:31]=1