6-Hydroxyindole → 6-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide
Reaction equation
[OH:1][C:2]1C=C2C(C=CN2)=[CH:4][CH:3]=1.C(O[C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([C:24]([NH2:26])=[O:25])[CH:19]=[C:18]2[N:27]=[C:28]=[O:29])C=C>>[CH2:2]([O:1][C:23]1[CH:22]=[C:21]2[C:17]([C:18]([N:27]=[C:28]=[O:29])=[CH:19][N:20]2[C:24]([NH2:26])=[O:25])=[CH:16][CH:15]=1)[CH:3]=[CH2:4]Participants
3
Procedure
was prepared from 6-hydroxy-indole using the protocol described for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide in Scheme A4.
Sources & evidence
- ORD record
- ord-fbd50c93916848f58b001992ba690a79
- Source dataset
- uspto-grants-2015_07
- Patent number
- US09085555B2
Reaction notes
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